I’m a Leo ascendant Sagittarius.
In 1998/1999 I met my current boyfriend, and in 1999 there was an unpleasant event that ultimately comes to my mind more than before. In 2008/2009 I left the family business to start my current activities and in the meantime I have lived, in the family, a difficult financial crisis fortunately successful. Currently I often find myself thinking that you want a child but I have certain economic problems to want to solve before making this big step; my job is a very creative job and I love, but I often find myself thinking that maybe I should join him at an economically safer work. All this baffles me because it seems really to touch the same points of the years that you’ve told us to regard (1998/99 – 2008/09).
Should I focus on everything myself?
Fixed the refs. Good find Louise and you are 100% correct about TGF (T = “transforming” not “tumor”). TGF beta3 is indeed the key to scarless healing. And while human amniotic fluid may be a good place to find some, that source has issues. meanwhile, we now know that mesenchymal stem cells in culture can produce this en masse. That is also part of the answer “where does TGF-beta3 come from? During embryonic life, many different types of cells are behaving like these stem cells (indeed embryos are by their nature mainly stem cells – makes sense from a developmental perspective). So during fetal life skin and other tissues make a lot of their own TGF beta-3 driven by the genetic imperative to develop into a infant human capable of surviving outside the womb. We gradually lose that capability over time (a strong correlate of aging itself). In adults, much of human regenerative capacity resides in these very special cells that live in the bone marrow but patrol the whole body looking for problems to solve (. wound healing). And because cytokines are a communication molecule, these stem cells not only tell other =cells what to do ( new healthy tissue) but also tell them to make more of the same molecule. Sort of a “tell a friend” scheme that amplifies the message in that tissue. There are other cytokines that tell tissue to grow, but TGF beta3 is unique in its ability to create scar-free (fetal-like) regeneration. Hope this sheds more light on the “where does it come from” question.