Here’s a working thesis with potential: you have highlighted an important aspect of the novel for investigation. However, it’s still not clear what your analysis will reveal. Your reader is intrigued but is still thinking, “So what? What’s the point of this contrast? What does it signify?” Perhaps you are not sure yet, either. That’s fine—begin to work on comparing scenes from the book and see what you discover. Free write, make lists, jot down Huck’s actions and reactions. Eventually you will be able to clarify for yourself, and then for the reader, why this contrast matters. After examining the evidence and considering your own insights, you write:
Research interests in the Bowdish lab including 1) understanding the role of macrophages in initial interactions with pathogens, with a focus on pulmonary pathogens, 2) determining how age related changes in the immune response contribute to increased susceptibility to infection and 3) elucidating the molecular mechanisms of non-opsonic phagocytosis and 4) developing novel immunomodulatory therapies to treat infectious disease. For more detailed descriptions of the research going on in the Bowdish lab see the “Current Projects” page.
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The Bowdish lab is located in the M. G. DeGroote Centre for Learning & Discovery at McMaster University in Hamilton, Ontario, Canada. We are part of the Department of Pathology and Molecular Medicine in the Faculty of Health Sciences and the Institute for Infectious Disease Research and the McMaster Immunology Research Centre . As such we have access to the state of the art facilities at McMaster including the Biophotonics facility , the High Throughput Screening Laboratory , the Human Immune Analysis Facility and the . Fitzhenry Vector Laboratory .
The long term goal of our work is to make major advances in our understanding of host defence against infectious disease. To do this we aspire to understand both the basic molecular and cellular biology of host-pathogen interactions, to utilize novel human models of disease and to find novel ways of translating our work into potential immunotherapies. The work in our lab is creative, innovative, ambitious and c ollaborative . We aim to be a resource to our colleagues and to train highly motivated students and post-docs to become world class scientists. We are always interested in hearing from motivated researchers who are interested in a career in infectious disease research.
This thesis presents TinkRBooks, interactive storybooks that support parent-child storytelling. TinkRBooks allow emergent readers to actively explore the abstract relationship between printed words and their meanings, even before this relationship is properly understood. Chang presents a new way of teaching the concept of reading, based on interactivity with story elements.
Using an iterative participatory design process, Chang presents a principled set of multisensory interaction guidelines for enabling emergent readers to alter the text-graphic relationship in storybooks during parent-child reading. She presents a novel software platform that dynamically links text with multisensory representations in response to vocal or haptic story interactions. The resulting experience invites emergent readers to modify and explore how text relates to concepts within a narrative.
This ability to explore textual representation changes the way parents read to their children during emergent literacy. When using a TinkRBook, parents spend more time talking, discussing more comprehensive ideas with their children and provoking more metadialogue than with regular books. TinkRBooks also encourage children to drive their reading inquiry, by actively demonstrating the concepts relating to vocabulary schema within the narrative. The result is a new story-sharing experience that benefits both parents and children by allowing them to understand how the choice of words impacts the story experience.